医药中间体
医药中间体
2017-10-16
 

欢迎观临我们的展位 CPHI 2018  W4E91 

项目名称

中文全称

英文名

CAS

化学名

依匹哌唑

依匹哌唑

Brexpiprazole

913611-97-9

7-[4-(4-苯并[b]噻吩-4--1-哌嗪)丁氧基]-2(1h)-喹啉酮

依匹哌唑中间体1

7-(4-chlorobutoxy)-1H-quinolin-2-one

913613-82-8

7-(4-氯丁氧基)-3,4-二氢-2(1H)-喹啉酮

依匹哌唑中间体2

1-(Benzo[b]thiophen-4-yl)piperazine

846038-18-4

1-(苯并[B]噻吩-4-)哌嗪

依匹哌唑 KSM1

4-BROMO-BENZO[B]THIOPHENE

5118-13-8

 4-溴苯并[B]噻吩

依匹哌唑 KSM2

7-Hydroxyquinolinone

70500-72-0

 7-羟基-2-喹诺酮

依匹哌唑 KSM3

4-chloro- Benzo[b]thiophene

66490-33-3

 4-氯苯并噻吩

赛乐西帕

赛乐西帕

2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide

475086-01-2

赛乐西帕;2-{4-[(5,6-二苯基吡嗪-2-)(异丙基)氨基]丁氧基}-N-(甲基磺酰基)乙酰胺

赛乐西帕中间体1

4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]-1-butanol

475086-75-0

[4-[(5,6-二苯基吡嗪基)(2-异丙基)氨基]-1-正丁醇

赛乐西帕中间体2

2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester

475084-96-9

2-{4-[N-(5,6-二苯基吡嗪基)-N_异丙基氨基]正丁氧基}乙酸叔丁醇酯

赛乐西帕中间体3

[4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID

475085-57-5

[4-[(5,6-二苯基吡嗪基)(1-甲基乙基)氨基]丁氧基]乙酸

赛乐西帕KSM 1

5-chloro-2,3-diphenylpyrazine

41270-66-0

5--2,3-二苯基哌嗪5--2,3-二苯基哌嗪

赛乐西帕KSM 2

4-(Isopropylamino)butanol

42042-71-7

4-(异丙基氨基)-1-丁醇

赛乐西帕KSM 3

5-Iodo-2,3-diphenylpyrazine

101727-15-5

5--2,3-二苯基吡嗪

氢溴酸沃替西汀

氢溴酸沃替西汀

Vortioxetine HBR

960203-27-4

1-[2-[(2,4-二甲基苯基)硫基]苯基]哌嗪氢溴酸盐

沃替西汀

Vortioxetine

508233-74-7

1-[2-(2,4-甲基苯硫基)苯基]哌嗪;1-(2-((2,4-二甲基苯基)硫代)苯基)哌嗪;4-[-2-(2,4-二甲基-苯硫烷基)-苯基-哌嗪

沃替西汀HBR KSM 2

(2,4-dimethylphenyl)(2-nitrophenyl)sulfane

1610527-49-5

2-(2,4-二甲基苯硫基 ) 硝基苯

沃替西汀HBR KSM 3

2-((2,4-dimethylphenyl)thio)aniline

1019453-85-0

2-((2,4-甲基苯基)硫代)苯胺

沃替西汀HBR KSM 1

1-[(2-BroMophenyl)thio]-2,4-diMethylbenzene

60203-41-2

1-[(2-溴苯基)硫基]-2,4-二甲基苯

乙磺酸尼达尼布

乙磺酸尼达尼布

nintedanib esylate(3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanecarboxylic Acid Methyl Ester

656247-18-6

(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯乙磺酸盐

乙磺酸尼达尼布

中间体1

1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester

1160293-25-3

1-(2-氯乙酰基)-2-氧代吲哚啉-6-羧酸甲酯

乙磺酸尼达尼布

中间体2

(E)-methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

1174335-83-1

 
(3E)-1-(2-
氯乙酰基)-2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯

乙磺酸尼达尼布

中间体3

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylicacid methyl ester

1168150-46-6

2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯

乙磺酸尼达尼布

中间体4

methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120)

656247-17-5

(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯

乙磺酸尼达尼布KSM1

Methyl oxindole-6-carboxylate

14192-26-8

2-氧化吲哚-6-甲酸甲酯

乙磺酸尼达尼布KSM2

N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide

262368-30-9

N-(4-氨基苯基)-N,4-二甲基-1-哌嗪乙酰胺

沃拉帕沙

沃拉帕沙

Vorapaxar Sulfate

705260-08-8

沃拉帕沙硫酸盐

沃拉帕沙中间体2

4-nitroheptanedial

147189-43-3

4-硝基庚二醛

沃拉帕沙中间体3

5-nitrocyclohexene-1-carbaldehyde

900186-75-6

5-硝基-1-环己烯-1-羧醛

沃拉帕沙中间体4

(E)-3-(5-nitrocyclohexen-1-yl)prop-2-enoic acid

899809-64-4

(E)-3-(5-硝基-1-环己烯-1-)丙烯酸

沃拉帕沙中间体5

N,N-diphenylimidazole-1-carboxamide

2875-79-8

N,N-二苯基-1H-咪唑甲酰胺

沃拉帕沙中间体6

(R)-4-hydroxy-N,N-diphenylpent-2-ynamide

899809-61-1

(4R)-4-羟基-N,N-二苯基-2-戊炔酰胺

沃拉帕沙中间体7

[(5-bromo-2-pyridinyl)methyl]-phosphonic acid diethyl ester;

380893-73-2

(5-溴吡啶-2-)甲基磷酸二乙酯

沃拉帕沙中间体8

[[5-(3-fluorophenyl)-2-pyridinyl]Methyl]-, diethyl ester

380894-77-9

二乙基((5-(3-氟苯基)吡啶-2-)甲基)磷酸酯

沃拉帕沙中间体9

(R)-5-(diphenylamino)-5-oxopent-3-yn-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate

899809-60-0

(2E)-3-(5-硝基-1-环己烯-1-)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁炔-1-基酯

沃拉帕沙中间体10

(R,E)-5-(diphenylamino)-5-oxopent-3-en-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate

900186-73-4

(2E)-3-(5-硝基-1-环己烯-1-)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁烯-1-基酯

沃拉帕沙中间体11

(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-Decahydro-3-methyl-7-nitro-1-oxo-N,N-diphenylnaphtho[2,3-c]furan-4-carboxamide

900186-72-3

(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-十氢-3-甲基-7-硝基-1-氧代-N,N-二苯基萘并[2,3-c]呋喃-4-甲酰胺

沃拉帕沙中间体12

[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(Diphenylamino)carbonyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic acid ethyl ester

900161-12-8

[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(二苯基氨基)羰基]十二氢-1-甲基-3-氧代萘并[2,3-c]呋喃-6-]氨基甲酸乙酯

盐酸阿考替胺

盐酸阿考替胺

Acotiamide Hydrochloride

773092-05-0

N -{2-[双(1-甲基乙基)氨基]乙基}-2-[ 2-羟基-4,5-二甲氨基苄基)胺]噻唑-4-酰胺 单盐酸盐三水合物

盐酸阿考替胺

中间体2

ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate

185105-98-0

2-[N-(2,4,5-三甲氧基苯甲酰基)氨基]-4-乙氧基羰基-1,3-噻唑

阿伐那非

阿伐那非

Avanafil

330784-47-9

4-[(3--4-甲氧基苄基)氨基]-2-[2-(羟甲基)-1-吡咯烷基]-N-(2-嘧啶基甲基)-5-嘧啶甲磺酰胺

阿伐那非

中间体2

ethyl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

330785-83-6

S-4-3--4-甲氧基苄基氨基)-5-乙氧羰基-2-2-羟甲基-1-吡咯烷基)嘧啶

阿伐那非

中间体3

(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

330785-84-7

S-4-3--4-甲氧基苄基氨基)-5-羧基-2-2-羟甲基-1-吡咯烷基)嘧啶

雷美替胺

雷美替胺

Ramelteon

196597-26-9

(S)-N-(2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙基)丙酰胺

雷美替胺中间体1

(E)-2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile

196597-79-2

E-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-亚基)乙腈

雷美替胺中间体2

2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine

448964-37-2

2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙胺

雷美替胺中间体3

(S)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-aminium chloride

196597-80-5

S-2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙胺盐酸盐

Brigatinib

Brigatinib

AP26113 (Brigatinib)

1197953-54-0

5--N2-[4-[4-(二甲基氨基)-1-哌啶基]-2-甲氧基苯基]-N4-[2-(二甲基亚膦酰)苯基]-2,4-嘧啶二胺

AP26113中间体4

[2-Methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amine

761440-75-9

 2-甲氧基-4-[4-(4-甲基-1-哌嗪基)-1-哌嗪基]-盐酸苯胺

AP26113中间体1

2,5-dichloro-N-(2-(diMethylphosphoryl)phenyl)pyriMidin-4-aMine

1197953-49-3

 AP26113中间体1

AP26113中间体

2-(diMethylphosphoryl)aniline

1197953-47-1

 2-(二甲基氧磷基)苯胺

AP26113中间体3

1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine

761440-65-7

 1-(1-(3-甲氧基-4-硝基苯基)哌啶-4-)-4-甲基哌嗪

阿可替尼

acalabrutinib

(S)-4-(8-amino-3-(1-but-2-ynoylpyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide

1420477-60-6

ACP-196苯甲酰胺, 4-[8-氨基-3-[(2S)-1-(1-氧代-2-丁炔-1-)-2-吡咯烷基]咪唑并[1,5-A]吡嗪-1-]-N-2-吡啶基-

Acalabrutinib

 中间体1;(ACAT-004

1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)-

1418307-17-1

1-Pyrrolidinecarboxylic acid, 2-[[[(3-chloro-2-pyrazinyl)methyl]amino]carbonyl]-, phenylmethyl ester, (2S)-

Acalabrutinib 中间体2ACAT-005

(S)-benzyl 2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate

1418307-18-2

 (S)-8--3-(N-CBZ-2-四氢吡咯基)咪唑[1,5]吡嗪

Acalabrutinib 中间体3ACAT-007

1-Pyrrolidinecarboxylic acid, 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-, phenylmethyl ester, (2S)-

1420478-88-1

 (S)-苯基 2-(8-氨基-1-溴咪唑[1,5-a]吡嗪-3-)吡咯烷-1-羧酸酯

Acalabrutinib 中间体4ACAT-008

4-(PYRIDIN-2-YL)AMINOCARBONYLPHENYLBORONIC ACID

850568-25-1

 4-(砒啶-2-)甲酰氨苯基硼酸

Acalabrutinib 中间体

(3-Chloropyrazin-2-yl)MethanaMine hydrochloride

939412-86-9

 (3-氯吡嗪-2-)甲胺盐酸

Abemaciclib

Abemaciclib base

N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine

1231929-97-7

LY2835219N-[5-[(4-乙基-1-哌嗪基)甲基]-2-吡啶基]-5--4-[4--2-甲基-1-异丙基-1H-苯并咪唑-6-]-2-嘧啶胺

Abemaciclib Mesylate

N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine

1231930-82-7

 N-[5-[(4-乙基-1-哌嗪基)甲基]-2-吡啶基]-5--4-[4--2-甲基-1-异丙基-1H-苯并咪唑-6-]-2-嘧啶胺甲烷磺酸盐

LY2835219中间体4

1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-

1231930-37-2

 1H-苯并咪唑, 4--2-甲基-1-(异丙基)-6-(4,4,5,5-四甲基-1,3,2-二氧杂环己硼烷-2-)-

LY2835219中间体KSM-1

1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-

1231930-42-9   

6-(2--5--嘧啶-4-)-4--1-异丙基-2-甲基-1H-苯并咪唑

LY2835219中间体6

KSM-2

5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine

1180132-17-5

 5-[(4-乙基哌嗪-1-)甲基]吡啶-2-

LY2835219中间体7

6-Aminonicotinaldehyde

69879-22-7

2-氨基-5-醛基吡啶

LY2835219中间体1

N-Isopropylacetamide

1118-69-0

N-异丙基乙酰胺

ABEMACICLIB中间体

EthaniMidaMide, N-(4-broMo-2,6-difluorophenyl)-N'-(1-Methylethyl)-

1231930-29-2

 N-(4--2,6-二氟-苯基)-N'-异丙基-乙酰胺

LY2835219中间体3

6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

1231930-33-8

 6--4--1-异丙基-2-甲基-1H-苯并[D]咪唑

LY2835219中间体5

1-((6-bromopyridin-3-yl)methyl)-4-ethylpiperazine

1231930-25-8

 1-[(6--3-吡啶基)甲基]-4-乙基-哌嗪

咪达那新

咪达那新

Imidafenacin

170105-16-5

4-(2-甲基-1H-咪唑-1-)-2,2-二苯基丁酰胺

咪达那新中间体1

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile

214777-43-2

4-2-甲基-1-咪唑基)-2,2-二苯基丁腈

咪达那新中间体2

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile phosphenoperoxoic acid

893421-55-1

4-2-甲基-1-咪唑基)-2,2-二苯基丁腈磷酸盐

咪达那新中间体3

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

893421-54-0

4-(2-甲基-1H-咪唑-1-)-2,2-二苯基丁酰胺盐酸盐

阿齐沙坦

阿齐沙坦

Azilsartan

147403-03-0

2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-)联苯-4-]甲基]苯并咪唑-7-羧酸

阿齐沙坦

中间体1

ethyl (Z)-2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

1397836-41-7

1-[(2'-(羟基脒基)[1,1-联苯基]-4-)甲基]-2-乙氧基-1H-苯并咪唑-7-羧酸乙酯

阿齐沙坦

中间体2

ethyl 2-ethoxy-1-((2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

1403474-70-3

2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-)联苯-4-]甲基]苯并咪唑-7-羧酸乙酯

盐酸考尼伐坦

盐酸考尼伐坦

Conivaptan hydrochloride

168626-94-6

[1,1' - 联苯] -2 - 甲酰胺,N-[4 - [4,5 - 二氢-2 - 甲基咪唑并[4,5-d[4]苯并氮杂-61H - 基)羰基]苯基] 盐酸盐

盐酸考尼伐坦

中间体2

4-([1,1'-biphenyl]-2-carboxamido)benzoic acid

168626-74-2

4-(联苯-2-酰胺基)苯甲酸

马西替坦

马西替坦

Macitentan

441798-33-0

N-[5-(4-溴苯基)-6-[2-[(5--2-嘧啶基)]乙氧基]-4-嘧啶基]-N'-丙基磺酰胺

马西替坦

中间体1

N-(5-(4-bromophenyl)-6-chloropyrimidin-4-yl)propane-1-sulfamide

1393813-42-7

N-5-4-溴苯基)-6-氯嘧啶-4-丙基磺酰胺

马西替坦

中间体2

N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide

1393813-43-8

N-5-4-溴苯基)-6-2-嘧啶-4-丙基磺酰胺

维拉唑酮

盐酸维拉佐酮

Vilazodone

163521-12-8

盐酸维拉佐酮

中间体1

5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxylic acid ethyl ester hydrochlorid

1422956-25-9

 

中间体2

5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid

163521-19-5

维拉佐酮羧基酸

托比司他

托比司他

2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-

577778-58-6

 

中间体1

4-Pyridinecarboxylicacid,2-cyano-,hydrazide

135048-32-7

2-氰基异烟酰肼

罗氟司特

罗氟司特

Roflumilast

162401-32-3

3-(环丙基甲氧基)-N-(3,5-二氯吡啶-4-)-4-(二氟甲氧基)苯甲酰胺

盐酸氯卡色林

盐酸氯卡色林

Lorcaserin hydrochloride

846589-98-8

(R)-8--1-甲基-2,3,4,5-四氢-1H-3-苯并氮杂卓盐酸盐

盐酸氯卡色林中间体1

1-((4-chlorophenethyl)amino)propan-2-ol

847063-13-2

1-[2-(4--苯基)-乙基氨基]-2-丙醇

盐酸氯卡色林中间体2

2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride

953789-37-2

1-[[2-(4-氯苯基)乙基]氨基]-2-氯丙烷盐酸盐

盐酸氯卡色林中间体3

8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

616201-80-0

8--1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓

盐酸氯卡色林中间体4

(R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine (2R,3R)-2,3-dihydroxysuccinate

847063-12-1

8--1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓半酒石酸盐

奥贝胆酸

6-乙基鹅去氧胆酸

6-Ethylchenodeoxycholic acid

459789-99-2

6-乙基鹅去氧胆酸

中间体1

(E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid methyl ester

863239-59-2

E/Z-3α羟基-6-亚乙基-7--5β-胆烷酸-24-甲酯

中间体2

3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid

915038-26-5

3α-羟基-6-乙基-7--5β--24-

哌啶甲酸

 

S-2—Pipecolinic Acid

3105-95-1

S-2-哌啶甲酸

帕布西利布

帕布西利布

Palbociclib isethionate

827022-33-3

帕布西利布羟基乙磺酸盐

帕布西利布中间体1

4-[6-[(6-Bromo-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

571188-82-4

4-[6-[(6--8-环戊基-7,8-二氢-5-甲基-7-氧代吡啶并[2,3-d]嘧啶-2-)氨基]-3-吡啶基]-1-哌嗪羧酸叔丁酯

帕布西利布中间体2

tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate (CAS No.866084-31-3)

866084-31-3

2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-]氨基} -3-吡啶基)-1-哌嗪甲酸

帕布西利布中间体3

6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one

571190-30-2

6-乙酰基-8-环戊基-5-甲基-2-[[5-(哌嗪-1-)吡啶-2-]氨基]-8H-吡啶并[2,3-D]嘧啶-7-

枸橼酸铁

枸橼酸铁

Ferric Citrate

3522-50-7

枸橼酸铁

甲苯磺酸依度沙班

甲苯磺酸依度沙班

Edoxaban TsOH salt

480449-71-6

依度沙班对甲苯磺酸盐

甲苯磺酸依度沙班

中间体1

tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate

480452-36-6

[(1R,2S,5S)-2-[[2-[(5-氯吡啶-2-)氨基]-2-氧代乙酰基]氨基]-5-(二甲基氨基羰基)环己基]氨基甲酸叔丁酯

甲苯磺酸依度沙班

中间体2

N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide

480449-70-5

N-(5--2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)乙酰基]-2-[[(4,5,6,7-四氢-5-甲基噻唑并[5,4-c]吡啶-2-)甲酰]氨基]环己基]乙二酰胺

磷酸特地唑胺

磷酸特地唑胺

TEDIZOLID PHOSPHATE-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate

856867-55-5

(R)-3-(4-(2-(2-甲基四唑-5-)吡啶-5-)-3-氟苯基)-5-羟甲基噁唑烷-2-酮磷酸酯

磷酸特地唑胺

中间体1

3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone

856866-72-3

3-[3--4-[6-(2-甲基-2H-四唑-5-)-3-吡啶基]苯基]-5-(羟基甲基)-2-恶唑烷酮

阿普斯特

阿普斯特

Apremilast(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

608141-41-9

(S)-2-[1-(3-乙氧基-4-甲氧基苯基)-2-甲磺酰基乙基]-4-乙酰基氨基异吲哚啉-1,3-二酮

阿普斯特

中间体1

(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt

608141-43-1

(S)-1-(3-乙氧基-4-甲氧基苯基)-2-(甲基磺酰基)乙胺 N-乙酰基-L-亮氨酸盐

枸橼酸托法替布

枸橼酸托法替布

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate

540737-29-9

3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-d]嘧啶-4-)氨基)哌啶-1-)-3-氧代丙腈,枸橼酸盐(11;

枸橼酸托法替布

中间体一

7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]-

923036-30-0

N-甲基-N-((3R,4R)-4-甲基-1-苄基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-

枸橼酸托法替布

中间体二

N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

477600-73-0

N-((3R,4R)-1-苄基-4-甲基哌啶-3-)-N-甲基-7H-吡咯[2,3-d]嘧啶-4-

枸橼酸托法替布

中间体三

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

477600-74-1

N-甲基-N-((3R,4R)-4-甲基哌啶-3-)-7H-吡咯并[2,3-D]嘧啶-4-

枸橼酸托法替布

中间体四

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

 477600-75-2

3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯[2,3-d]嘧啶-4-)胺基)哌啶-1-)-3-氧代丙腈

甲磺酸伊马替尼

甲磺酸伊马替尼

N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate

220127-57-1

4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺甲磺酸盐

中间体1(即伊马替尼游离碱)

N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide

152459-95-5

4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺

福沙匹坦

福沙匹坦

D-Glucitol, 1-deoxy-1-(methylamino)-, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4- morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate (2:1)

265121-04-8

1-脱氧-1-(甲基氨基)-D-葡萄糖醇 [3-[[(2R,3S)-2-[(1R)-1-[3,5-(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)-4-吗啉基]甲基]-2,5-二氢-5-氧代-1H-1,2,4-三唑-1-]膦酸盐

中间体1(即阿瑞匹坦)

5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one

170729-80-3

5-[2(R)-[1(R)-[3,5-(三氟甲基)苯基]乙氧基]-3(S)-(4-氟苯基)吗啉-4-基甲基]-3,4-二氢-2H-1,2,4-三唑-3-

中间体2(福沙匹坦单卞酯)

benzyl hydrogen (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate

889852-02-2

3-[[(2R,3S)-2-[(1R)-1-[3,5-(三氟甲基)苯基]乙氧基] -3-(4-氟苯基)-4-吗啉基]甲基] -25-二氢-5-氧代-1H-1,2,4-三氮唑-1-]膦酸单苄酯

盐酸他喷他多

盐酸他喷他多

3-((2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl)phenol hydrochloride

175591-09-0

(-)-(1R,2R)-3-(3-二甲氨基-1-乙基-2-甲基丙基)苯酚盐酸盐

中间体1

3-(1-dimethylamino-2-methyl-pentan-3-yl)phenol

175591-23-8

3-((1R,2R)-3-(二甲基氨基)-1-乙基-2-甲基丙基)苯酚

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