医药中间体
医药中间体
2017-05-11

欢迎观临我们的展位 CPHI 2017  T5A22 

项目

名称

中文全称

英文名

CAS

化学名

咪达

那新

咪达那新

Imidafenacin

170105-16-5

4-(2-甲基-1H-咪唑-1-)-2,2-二苯基丁酰胺

中间体1

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile

214777-43-2

4-2-甲基-1-咪唑基)-2,2-二苯基丁腈

中间体2

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanenitrile phosphenoperoxoic acid

893421-55-1

4-2-甲基-1-咪唑基)-2,2-二苯基丁腈磷酸盐

中间体3

4-(2-methyl-1H-imidazol-1-yl)-2,2-diphenylbutanamide hydrochloride

893421-54-0

4-(2-甲基-1H-咪唑-1-)-2,2-二苯基丁酰胺盐酸盐

盐酸阿考替胺

盐酸阿考替胺

Acotiamide Hydrochloride

773092-05-0

N -{2-[双(1-甲基乙基)氨基]乙基}-2-[ 2-羟基-4,5-二甲氨基苄基)胺]噻唑-4-酰胺 单盐酸盐三水合物

中间体2

ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate

185105-98-0

2-[N-(2,4,5-三甲氧基苯甲酰基)氨基]-4-乙氧基羰基-1,3-噻唑

阿齐

沙坦

阿齐沙坦

Azilsartan

147403-03-0

2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-)联苯-4-]甲基]苯并咪唑-7-羧酸

中间体1

ethyl (Z)-2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

1397836-41-7

1-[(2'-(羟基脒基)[1,1-联苯基]-4-)甲基]-2-乙氧基-1H-苯并咪唑-7-羧酸乙酯

中间体2

ethyl 2-ethoxy-1-((2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

1403474-70-3

2-乙氧基-1-[[2'-(4,5-二氢-5-氧代-1,2,4-恶二唑-3-)联苯-4-]甲基]苯并咪唑-7-羧酸乙酯

阿伐那非

阿伐那非

Avanafil

330784-47-9

4-[(3--4-甲氧基苄基)氨基]-2-[2-(羟甲基)-1-吡咯烷基]-N-(2-嘧啶基甲基)-5-嘧啶甲磺酰胺

中间体2

ethyl (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylate

330785-83-6

S-4-3--4-甲氧基苄基氨基)-5-乙氧羰基-2-2-羟甲基-1-吡咯烷基)嘧啶

中间体3

(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)pyrimidine-5-carboxylic acid

330785-84-7

S-4-3--4-甲氧基苄基氨基)-5-羧基-2-2-羟甲基-1-吡咯烷基)嘧啶

盐酸考尼伐坦

盐酸考尼伐坦

Conivaptan hydrochloride

168626-94-6

[1,1' - 联苯] -2 - 甲酰胺,N-[4 - [4,5 - 二氢-2 - 甲基咪唑并[4,5-d[4]苯并氮杂-61H - 基)羰基]苯基] 盐酸盐

中间体2

4-([1,1'-biphenyl]-2-carboxamido)benzoic acid

168626-74-2

4-(联苯-2-酰胺基)苯甲酸

马西替坦

马西替坦

Macitentan

441798-33-0

N-[5-(4-溴苯基)-6-[2-[(5--2-嘧啶基)]乙氧基]-4-嘧啶基]-N'-丙基磺酰胺

中间体1

N-(5-(4-bromophenyl)-6-chloropyrimidin-4-yl)propane-1-sulfamide

1393813-42-7

N-5-4-溴苯基)-6-氯嘧啶-4-丙基磺酰胺

中间体2

N-(5-(4-bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide

1393813-43-8

N-5-4-溴苯基)-6-2-嘧啶-4-丙基磺酰胺

伊曲茶碱

伊曲茶碱

Istradefylline

155270-99-8

8-[(E)-2-(3,4-二甲氧基苯基)乙烯基]-1,3-二乙基-7-甲基嘌呤-2,6-二酮

中间体一

6-amino-1,3-diethylpyrimidine-2,4(1H,3H)-dione

41740-15-2

6-氨基-1,3-二乙基-2,4(1H,3H)-嘧啶二酮

中间体二

5,6-diamino-1,3-diethylpyrimidine-2,4(1H,3H)-dione

52998-22-8

 

中间体三

(E)-N-(6-aMino-1,3-diethyl-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-5-yl)-3-(3,4-diMethoxyphenyl)acrylaMide

187393-68-6

E)-1,3-二乙基-6-氨基-5-(3,4-二甲氧基苯丙烯酰基)氨基尿嘧啶

中间体四

8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,9-dihydro-1H-purine-2,6-dione

155270-98-7

8-[(1E)-2-(3,4-二甲氧基苯基)乙烯基]-1,3-二乙基-3,9-二氢-1H-嘌呤-2,6-二酮

泊马度胺

泊马度胺

Pomalidomide

19171-19-8

3-氨基-N-(2,6-二氧-3-哌啶基)苯邻二甲酰亚胺

中间体一

1,3-Isobenzofurandione,4-amino

17395-99-2

1,3-异苯并,4-氨基

氢溴酸沃替西汀

氢溴酸沃替西汀

Vortioxetine HBR

960203-27-4

1-[2-[(2,4-二甲基苯基)硫基]苯基]哌嗪氢溴酸盐

沃替西汀

Vortioxetine

508233-74-7

1-[2-(2,4-甲基苯硫基)苯基]哌嗪;1-(2-((2,4-二甲基苯基)硫代)苯基)哌嗪;4-[-2-(2,4-二甲基-苯硫烷基)-苯基-哌嗪

中间体1

(2,4-dimethylphenyl)(2-nitrophenyl)sulfane

1610527-49-5

2-(2,4-二甲基苯硫基 ) 硝基苯

中间体2

2-((2,4-dimethylphenyl)thio)aniline

1019453-85-0

2-((2,4-甲基苯基)硫代)苯胺

维拉唑酮

盐酸维拉佐酮

Vilazodone

163521-12-8

盐酸维拉佐酮

中间体1

5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxylic acid ethyl ester hydrochlorid

1422956-25-9

 

中间体2

5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-Benzofurancarboxylic acid

163521-19-5

维拉佐酮羧基酸

托比司他

托比司他

2-Pyridinecarbonitrile, 4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-

577778-58-6

 

中间体1

 4-Pyridinecarboxylicacid,2-cyano-,hydrazide

135048-32-7

2-氰基异烟酰肼

罗氟司特

罗氟司特

Roflumilast

162401-32-3

3-(环丙基甲氧基)-N-(3,5-二氯吡啶-4-)-4-(二氟甲氧基)苯甲酰胺

雷美替胺

雷美替胺

Ramelteon

196597-26-9

(S)-N-(2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙基)丙酰胺

中间体1

(E)-2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile

196597-79-2

E-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-亚基)乙腈

中间体2

2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-amine

448964-37-2

2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙胺

中间体3

(S)-2-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethan-1-aminium chloride

196597-80-5

S-2-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-)乙胺盐酸盐

盐酸氯卡色林

盐酸氯卡色林

Lorcaserin hydrochloride

846589-98-8

(R)-8--1-甲基-2,3,4,5-四氢-1H-3-苯并氮杂卓盐酸盐

中间体1

1-((4-chlorophenethyl)amino)propan-2-ol

847063-13-2

1-[2-(4--苯基)-乙基氨基]-2-丙醇

中间体2

2-chloro-N-(4-chlorophenethyl)propan-1-amine hydrochloride

953789-37-2

1-[[2-(4-氯苯基)乙基]氨基]-2-氯丙烷盐酸盐

中间体3

8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

616201-80-0

8--1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓

中间体4

(R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine (2R,3R)-2,3-dihydroxysuccinate

847063-12-1

8--1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂卓半酒石酸盐

沃拉帕沙

沃拉帕沙

Vorapaxar Sulfate

705260-08-8

沃拉帕沙硫酸盐

中间体2

4-nitroheptanedial

147189-43-3

4-硝基庚二醛

中间体3

5-nitrocyclohexene-1-carbaldehyde

900186-75-6

5-硝基-1-环己烯-1-羧醛

中间体4

(E)-3-(5-nitrocyclohexen-1-yl)prop-2-enoic acid

899809-64-4

(E)-3-(5-硝基-1-环己烯-1-)丙烯酸

中间体5

N,N-diphenylimidazole-1-carboxamide

2875-79-8

N,N-二苯基-1H-咪唑甲酰胺

中间体6

(R)-4-hydroxy-N,N-diphenylpent-2-ynamide

899809-61-1

(4R)-4-羟基-N,N-二苯基-2-戊炔酰胺

中间体7

 
[(5-bromo-2-pyridinyl)methyl]-phosphonic acid diethyl ester;

380893-73-2

(5-溴吡啶-2-)甲基磷酸二乙酯

中间体8

[[5-(3-fluorophenyl)-2-pyridinyl]Methyl]-, diethyl ester

380894-77-9

二乙基((5-(3-氟苯基)吡啶-2-)甲基)磷酸酯

中间体9

(R)-5-(diphenylamino)-5-oxopent-3-yn-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate

899809-60-0

(2E)-3-(5-硝基-1-环己烯-1-)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁炔-1-基酯

中间体10

(R,E)-5-(diphenylamino)-5-oxopent-3-en-2-yl (E)-3-(5-nitrocyclohex-1-en-1-yl)acrylate

900186-73-4

(2E)-3-(5-硝基-1-环己烯-1-)-2-丙烯酸 (1R,2Z)-4-(二苯基氨基)-1-甲基-4-氧代-2-丁烯-1-基酯

中间体11

(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-Decahydro-3-methyl-7-nitro-1-oxo-N,N-diphenylnaphtho[2,3-c]furan-4-carboxamide

900186-72-3

(3R,3aS,4S,4aS,7R,9aR)-1,3,3a,4,4a,5,6,7,8,9a-十氢-3-甲基-7-硝基-1-氧代-N,N-二苯基萘并[2,3-c]呋喃-4-甲酰胺

中间体12

[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(Diphenylamino)carbonyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic acid ethyl ester

900161-12-8

[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(二苯基氨基)羰基]十二氢-1-甲基-3-氧代萘并[2,3-c]呋喃-6-]氨基甲酸乙酯

奥贝胆酸

6-乙基鹅去氧胆酸

6-Ethylchenodeoxycholic acid

459789-99-2

6-乙基鹅去氧胆酸

中间体1

(E/Z)-3α-hydroxy-6-ethylidene-7-keto-5β-cholan-24-oic acid methyl ester

863239-59-2

E/Z-3α羟基-6-亚乙基-7--5β-胆烷酸-24-甲酯

中间体2

3α-hydroxy-6-ethyl-7-keto-5β-cholan-24-oic acid

915038-26-5

3α-羟基-6-乙基-7--5β--24-

依匹哌唑

依匹哌唑

Brexpiprazole

913611-97-9

7-[4-(4-苯并[b]噻吩-4--1-哌嗪)丁氧基]-2(1h)-喹啉酮

中间体1

7-(4-chlorobutoxy)-1H-quinolin-2-one

913613-82-8

7-(4-氯丁氧基)-3,4-二氢-2(1H)-喹啉酮

中间体2

1-(Benzo[b]thiophen-4-yl)piperazine

846038-18-4

1-(苯并[B]噻吩-4-)哌嗪

selexipag

selexipag

2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide

475086-01-2

赛乐西帕;2-{4-[(5,6-二苯基吡嗪-2-)(异丙基)
氨基]丁氧基}-N-(甲基磺酰基)乙酰胺

中间体1

4-[(5,6-diphenylpyrazin-2-yl)(isopropyl)amino]-1-butanol

475086-75-0

[4-[(5,6-二苯基吡嗪基)
(2-
异丙基)氨基]-1-正丁醇

中间体2

2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester

475084-96-9

2-{4-[N-(5,6-二苯基吡嗪基)-N_异丙基氨基]正丁氧基}乙酸叔丁醇酯

中间体3

[4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID

475085-57-5

[4-[(5,6-二苯基吡嗪基)
(1-
甲基乙基)氨基]丁氧基]乙酸

哌啶甲酸

 

S-2—Pipecolinic Acid

3105-95-1

S-2-哌啶甲酸

乙磺酸尼达尼布

乙磺酸尼达尼布

nintedanib esylate(3S,5S)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1-hydroxy-cyclohexanecarboxylic Acid Methyl Ester

656247-18-6

(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯乙磺酸盐

中间体1

1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester

1160293-25-3

1-(2-氯乙酰基)-2-氧代吲哚啉-6-羧酸甲酯

中间体2

(E)-methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

1174335-83-1

 
(3E)-1-(2-
氯乙酰基)-2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯

中间体3

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylicacid methyl ester

1168150-46-6

2,3-二氢-3-(甲氧基苯基亚甲基)-2-氧代-1H-吲哚-6-羧酸甲酯

中间体4

methyl (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate Nintedanib (BIBF 1120)

656247-17-5

(3Z)-2,3-二氢-3-[[[4-[甲基[2-(4-甲基-1-哌嗪基)乙酰]氨基]苯基]氨基]苯亚甲基]-2-氧代-1H-吲哚-6-甲酸甲酯

帕布西利布

palbocicilb

Palbociclib isethionate

827022-33-3

帕布西利布羟基乙磺酸盐

中间体1

4-[6-[(6-Bromo-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

571188-82-4

4-[6-[(6--8-环戊基-7,8-二氢-5-甲基-7-氧代吡啶并[2,3-d]嘧啶-2-)氨基]-3-吡啶基]-1-哌嗪羧酸叔丁酯

中间体2

tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate (CAS No.866084-31-3)

866084-31-3

2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-]氨基} -3-吡啶基)-1-哌嗪甲酸

中间体3

6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one

571190-30-2

6-乙酰基-8-环戊基-5-甲基-2-[[5-(哌嗪-1-)吡啶-2-]氨基]-8H-吡啶并[2,3-D]嘧啶-7-

枸橼酸铁

枸橼酸铁

Ferric Citrate

3522-50-7

枸橼酸铁

甲苯磺酸依度沙班

甲苯磺酸依度沙班

Edoxaban TsOH salt

480449-71-6

依度沙班对甲苯磺酸盐

中间体1

tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate

480452-36-6

[(1R,2S,5S)-2-[[2-[(5-氯吡啶-2-)氨基]-2-氧代乙酰基]氨基]-5-(二甲基氨基羰基)环己基]氨基甲酸叔丁酯

中间体2

N-(5-Chloro-2-pyridinyl)-N'-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide

480449-70-5

N-(5--2-吡啶基)-N'-[(1S,2R,4S)-4-[(二甲基氨基)乙酰基]-2-[[(4,5,6,7-四氢-5-甲基噻唑并[5,4-c]吡啶-2-)甲酰]氨基]环己基]乙二酰胺

磷酸特地唑胺

磷酸特地唑胺

TEDIZOLID PHOSPHATE-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate

856867-55-5

(R)-3-(4-(2-(2-甲基四唑-5-)吡啶-5-)-3-氟苯基)-5-羟甲基噁唑烷-2-酮磷酸酯

中间体1

3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone

856866-72-3

3-[3--4-[6-(2-甲基-2H-四唑-5-)-3-吡啶基]苯基]-5-(羟基甲基)-2-恶唑烷酮

阿普斯特

阿普斯特

Apremilast(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

608141-41-9

(S)-2-[1-(3-乙氧基-4-甲氧基苯基)-2-甲磺酰基乙基]-4-乙酰基氨基异吲哚啉-1,3-二酮

中间体1

(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine N-acetyl-L-leucine salt

608141-43-1

(S)-1-(3-乙氧基-4-甲氧基苯基)-2-(甲基磺酰基)乙胺 N-乙酰基-L-亮氨酸盐

枸橼酸托法替布

枸橼酸托法替布

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile 2-hydroxypropane-1,2,3-tricarboxylate

540737-29-9

3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-d]嘧啶-4-)氨基)哌啶-1-)-3-氧代丙腈,枸橼酸盐(11;

中间体一

7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-1-(phenylMethyl)-3-piperidinyl]-7-[(4-Met hylphenyl)sulfonyl]-

923036-30-0

N-甲基-N-((3R,4R)-4-甲基-1-苄基-3-哌啶基)-7H-吡咯并[2,3-D]嘧啶-4-

中间体二

N-((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

477600-73-0

N-((3R,4R)-1-苄基-4-甲基哌啶-3-)-N-甲基-7H-吡咯[2,3-d]嘧啶-4-

中间体三

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

477600-74-1

N-甲基-N-((3R,4R)-4-甲基哌啶-3-)-7H-吡咯并[2,3-D]嘧啶-4-

中间体四

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

 477600-75-2

3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯[2,3-d]嘧啶-4-)胺基)哌啶-1-)-3-氧代丙腈

甲磺酸伊马替尼

甲磺酸伊马替尼

N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide methanesulfonate

220127-57-1

4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺甲磺酸盐

中间体1(即伊马替尼游离碱)

N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide

152459-95-5

4-[(4-甲基-1-哌嗪基)甲基]-N-[4-甲基-3-[4-(3-吡啶基)-2-嘧啶基]氨基]苯基]苯甲酰胺

福沙匹坦

福沙匹坦

D-Glucitol, 1-deoxy-1-(methylamino)-, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4- morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate (2:1)

265121-04-8

1-脱氧-1-(甲基氨基)-D-葡萄糖醇 [3-[[(2R,3S)-2-[(1R)-1-[3,5-(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)-4-吗啉基]甲基]-2,5-二氢-5-氧代-1H-1,2,4-三唑-1-]膦酸盐

中间体1(即阿瑞匹坦)

5-[2(r)-[1(r)-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3(s)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2h-1,2,4-triazol-3-one

170729-80-3

5-[2(R)-[1(R)-[3,5-(三氟甲基)苯基]乙氧基]-3(S)-(4-氟苯基)吗啉-4-基甲基]-3,4-二氢-2H-1,2,4-三唑-3-

中间体2(福沙匹坦单卞酯)

benzyl hydrogen (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate

889852-02-2

3-[[(2R,3S)-2-[(1R)-1-[3,5-(三氟甲基)苯基]乙氧基] -3-(4-氟苯基)-4-吗啉基]甲基] -25-二氢-5-氧代-1H-1,2,4-三氮唑-1-]膦酸单苄酯

盐酸他喷他多

盐酸他喷他多

3-((2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl)phenol hydrochloride

175591-09-0

(-)-(1R,2R)-3-(3-二甲氨基-1-乙基-2-甲基丙基)苯酚盐酸盐

中间体1

3-(1-dimethylamino-2-methyl-pentan-3-yl)phenol

175591-23-8

3-((1R,2R)-3-(二甲基氨基)-1-乙基-2-甲基丙基)苯酚

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